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ingenuity pathway analysis (ipa) knowledge-based database graphical user interface  (Qiagen)


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    Qiagen ingenuity pathway analysis (ipa) knowledge-based database graphical user interface
    Ingenuity Pathway Analysis (Ipa) Knowledge Based Database Graphical User Interface, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ingenuity+pathways+knowledge+base+(ipa)/ingenuity+pathway+analysis/pm40073243-60-21-25
    Average 90 stars, based on 1 article reviews
    ingenuity pathway analysis (ipa) knowledge-based database graphical user interface - by Bioz Stars, 2026-09
    90/100 stars

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    other:

    Article Title: Differences in gene expression between high and low tolerance rainbow trout ( Oncorhynchus mykiss ) to acute thermal stress
    Article Snippet: To address goal 4, we first identified canonical pathways and major upstream regulatory genes and their functions affecting thermal tolerance based upon predictive mammalian gene interaction networks as determined by the QIAGEN Ingenuity Pathways Knowledge Base (IPA) [ ] (RRID:SCR_008117).

    Indirect Immunoperoxidase Assay:

    Article Title: Differences in gene expression between high and low tolerance rainbow trout (Oncorhynchus mykiss) to acute thermal stress.
    Article Snippet: .. Identifying gene function via pathways and upstream regulatory genes To address goal 4, we first identified canonical pathways and major upstream regulatory genes and their functions affecting thermal tolerance based upon predictive mammalian gene interaction networks as determined by the QIAGEN Ingenuity Pathways Knowledge Base (IPA) [62] (RRID:SCR_008117). ..



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    Identification <t>of</t> <t>pathways</t> and upstream regulators modified by PPRV infections at 72 hpi. Qiagen’s <t>IPA</t> software provided a Zscore that informs on the activation status of pathways (A) and upstream regulators (B) . Positive zscores (upregulated) are represented by an orange gradient while negative zscores (downregulated) are represented by a blue gradient. Pathways and upstream regulators have been classified in categories related to antiviral cell responses (dark blue square), MAPK signalling (light blue square), lipid metabolism (yellow square), cell death, survival (violet square) and proliferation (green square).
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    Identification of pathways and upstream regulators modified by PPRV infections at 72 hpi. Qiagen’s IPA software provided a Zscore that informs on the activation status of pathways (A) and upstream regulators (B) . Positive zscores (upregulated) are represented by an orange gradient while negative zscores (downregulated) are represented by a blue gradient. Pathways and upstream regulators have been classified in categories related to antiviral cell responses (dark blue square), MAPK signalling (light blue square), lipid metabolism (yellow square), cell death, survival (violet square) and proliferation (green square).

    Journal: Frontiers in Immunology

    Article Title: Identification of Differential Responses of Goat PBMCs to PPRV Virulence Using a Multi-Omics Approach

    doi: 10.3389/fimmu.2021.745315

    Figure Lengend Snippet: Identification of pathways and upstream regulators modified by PPRV infections at 72 hpi. Qiagen’s IPA software provided a Zscore that informs on the activation status of pathways (A) and upstream regulators (B) . Positive zscores (upregulated) are represented by an orange gradient while negative zscores (downregulated) are represented by a blue gradient. Pathways and upstream regulators have been classified in categories related to antiviral cell responses (dark blue square), MAPK signalling (light blue square), lipid metabolism (yellow square), cell death, survival (violet square) and proliferation (green square).

    Article Snippet: Ingenuity Pathways Knowledge Base in QIAGEN’s IPA software (QIAGEN, Redwood City, USA) was used with the lists of differentially expressed genes to identify the canonical pathways, upstream regulators and the most significant biological processes.

    Techniques: Modification, Software, Activation Assay

    Analysis of the activation of biofunctions and BTMs during PPRV infections at 72 hpi. Activated (A) and inactivated (B) biofunctions were found during the analysis. Qiagen’s IPA software provided a zscore that determines the activation (zscore>2) and the inactivation (zscore<-2) status of biological functions. All inactivated functions represent virus infection and replication functions and therefore reflect the induction of antiviral activities in the cells. (C) Analysis of goat blood transcriptional modules (BTMs) during PPRV infections of PBMCs at 72 hpi. Goat BTMs were activated or inactivated during infections (significance level: FDR < 0.1). Positive normalised enrichment score (NES > 0) means activation of a set of genes while negative NES (NES < 0) means inactivation.

    Journal: Frontiers in Immunology

    Article Title: Identification of Differential Responses of Goat PBMCs to PPRV Virulence Using a Multi-Omics Approach

    doi: 10.3389/fimmu.2021.745315

    Figure Lengend Snippet: Analysis of the activation of biofunctions and BTMs during PPRV infections at 72 hpi. Activated (A) and inactivated (B) biofunctions were found during the analysis. Qiagen’s IPA software provided a zscore that determines the activation (zscore>2) and the inactivation (zscore<-2) status of biological functions. All inactivated functions represent virus infection and replication functions and therefore reflect the induction of antiviral activities in the cells. (C) Analysis of goat blood transcriptional modules (BTMs) during PPRV infections of PBMCs at 72 hpi. Goat BTMs were activated or inactivated during infections (significance level: FDR < 0.1). Positive normalised enrichment score (NES > 0) means activation of a set of genes while negative NES (NES < 0) means inactivation.

    Article Snippet: Ingenuity Pathways Knowledge Base in QIAGEN’s IPA software (QIAGEN, Redwood City, USA) was used with the lists of differentially expressed genes to identify the canonical pathways, upstream regulators and the most significant biological processes.

    Techniques: Activation Assay, Software, Virus, Infection